Other parents insist cannabis is helping their children when, in her view, it clearly isn’t — and they refuse to stop using it when they should move on to other treatments. “Because of all the hype, people somehow think this is a cure-all and a treatment that will fix everything,” she told me. What’s lost on many, she says, is that even if CBD helps, it’s still just another drug, and no drug works for everyone all the time. It’s reasonable to ask why the CBD naturally present in cannabis doesn’t protect recreational users from the negative effects of THC.
So have cases where epilepsy and spasmodic conditions like multiple sclerosis saw improvements after CBD was introduced to the system. So CBD has potential as an anticonvulsant, anti-inflammatory, and of course, an anti-anxiety supplement.
Precipitated Opioid Withdrawal And Cbd
Despite the noted differences between CBD and THC, the presence of both cannabinoids appear to balance the effects. Jacobson and other parents I spoke with argue that in difficult medical cases, doctors are already tinkering with potentially toxic drugs, so why can’t they — the parents or the patients — experiment with a less-toxic product?
Scientists could search for signals on what to study in this sea of self-experimentation. One reason some physicians look askance at the vernacular cannabis movement is that it can, in its sometimes quasi-religious devotion to the plant, seem almost cultlike.
Kristen Park, an epileptologist at Children’s Hospital in Colorado, told me that after Gupta’s CNN story aired, patients from around the country seeking medical cannabis inundated the hospital. She had no data at that point on its efficacy and did not recommend it.
In older varieties, where the CBD-to-THC ratio was closer to 1-to-1, maybe it did. When scientists at the French pharmaceutical company Sanofi-Aventis understood that THC could whet a user’s appetite, they created a weight-loss drug that blocked CB1 receptors, hoping to suppress appetite. Two years later, regulators pulled it from the marketplace because of its severe side effects, including depression and suicidal behavior. The episode seems to exemplify endocannabinoids’ importance to our sense of well-being and the difficulty of manipulating them therapeutically.
The Epidiolex trials have provided some evidence of effectiveness, Park told me, but she still frets over the phenomenon. Sometimes parents of patients refuse established epilepsy treatments in favor of cannabis products, she says, because these are perceived as somehow natural and thus superior to standard medicines.
- Another study that gave both THC and CBD oil to mice with symptoms of Alzheimer’s disease showed an improved in learning and had less evidence of amyloid clumps in their bodies.
- But more research is needed to understand the long-term effects of taking cannabis, and whether it is an effective and safe way to tackle dementia symptoms.
- If you have any questions or concerns about cannabis use and the risk of dementia or other brain disorders, please talk to your GP.
How Cbd Oil Works Best For You
Attempts to increase native cannabinoids with synthetic drugs have fared no better. In 2016, French scientists halted a study of a drug designed to boost endocannabinoids. For reasons that remain unclear, six patients who took the medicine, meant to treat pain, were hospitalized. When CBD binds to TRPV1 receptors, it plays a positive role in the regulation of body temperature, inflammation and pain tolerance. CBD’s potential for the treatment of chronic pain is a particular area of interest CBD oil for researchers.